Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614824 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A3HSP90AA1ALDH1A1HPGD | |
| SCHEMBL11728796 | 0.77 | MEN1 (0.38) | ALDH1A1HPGDGLAKMT2AMEN1 | |
| SCHEMBL4939421 | 0.75 | SLC6A3 (0.77) | SLC6A2SLC6A3HSP90AA1 | |
| SCHEMBL4935570 | 0.75 | SLC6A3 (0.63) | SLC6A2SLC6A3HSP90AA1LMNA | |
| SCHEMBL18519293 | 0.74 | RECQL (0.36) | ALDH1A1HPGDGLAKMT2AMEN1 | |
| SCHEMBL11665417 | 0.74 | SLC6A3 (0.75) | SLC6A2SLC6A3HSP90AA1ALDH1A1KMT2A | |
| SCHEMBL4313458 | 0.73 | HSP90AA1 (0.59) | SLC6A2SLC6A3HSP90AA1 | |
| SCHEMBL8431652 | 0.73 | SLC6A3 (0.53) | SLC6A2SLC6A3HSP90AA1ALDH1A1SCN1A | |
| SCHEMBL28571252 | 0.70 | SLC6A2 (0.46) | SLC6A2SLC6A3HSP90AA1ALDH1A1KMT2A | |
| SCHEMBL501353 | 0.69 | HSD17B10 (0.61) | SLC6A2SLC6A3HSP90AA1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112103-A | Antiarrhythmic (+,-)-cis-α-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanols | PARKE, DAVIS & COMPANY (US) | 1978-09-05 | — | — | US | disclosed |