Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 4/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18939488 | 0.85 | ACE (0.42) | MEN1KMT2AALDH1A1GLAHPGD | |
| SCHEMBL18519293 | 0.85 | RECQL (0.36) | MEN1KMT2AALDH1A1GLAHPGD | |
| SCHEMBL28751706 | 0.81 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1GLAHPGD | |
| SCHEMBL11614822 | 0.77 | SLC6A2 (0.50) | MEN1KMT2AALDH1A1GLAHPGD | |
| SCHEMBL11614824 | 0.77 | SLC6A2 (0.50) | MEN1KMT2AALDH1A1GLAHPGD | |
| SCHEMBL27822771 | 0.77 | RECQL (0.36) | KMT2AALDH1A1GLAHPGDRECQL | |
| SCHEMBL27800027 | 0.77 | KDM4E (0.50) | MEN1KMT2AALDH1A1HPGDRECQL | |
| SCHEMBL27800028 | 0.77 | KDM4E (0.50) | MEN1KMT2AALDH1A1HPGDRECQL | |
| SCHEMBL28751696 | 0.76 | HRH3 (0.39) | ALDH1A1ACE | |
| SCHEMBL28751694 | 0.75 | FFAR4 (0.39) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031101-A | ANTIARRHYTHMIA AGENT | PARKE, DAVIS & COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-4031101-A | ANTIARRHYTHMIA AGENT | PARKE, DAVIS & COMPANY (US) | 1977-06-21 | — | — | US | disclosed |