Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810676 | 0.77 | PTGS2 (0.57) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7682901 | 0.76 | PTGS2 (0.44) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11813807 | 0.69 | PTGS2 (0.71) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11808793 | 0.67 | ABCB11 (0.51) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1258744 | 0.63 | KMT2A (0.59) | LMNAMEN1KMT2ARAB9A | |
| SCHEMBL121475 | 0.63 | HPGD (0.66) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11711174 | 0.62 | PTGS2 (0.41) | HPGDLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7678562 | 0.62 | PTGS2 (0.57) | HPGDLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11814755 | 0.62 | PTGS2 (0.56) | HPGDLMNASMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL7674536 | 0.62 | PTGS2 (0.57) | HPGDLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070368-A | ACYLATION, DECARBOXYLATION | MCNEIL LABORATORIES, INCORPORATED (US) | 1978-01-24 | — | — | US | disclosed |