Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619251 | 0.86 | SLC22A12 (0.51) | SLC22A12ALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL11614807 | 0.70 | PTGDR2 (0.42) | PTGDR2GAAKMT2AHTTMAPT | |
| SCHEMBL3177634 | 0.68 | SLC22A12 (0.54) | SLC22A12MAPTTDP1 | |
| SCHEMBL11464795 | 0.68 | NPBWR1 (0.41) | SLC22A12PTGDR2ALDH1A1LMNAHPGD | |
| SCHEMBL15512442 | 0.66 | CMA1 (0.50) | SLC22A12ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL11508658 | 0.66 | MAPT (0.45) | SLC22A12LMNAHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL20881992 | 0.65 | TSHR (0.48) | ALDH1A1GAALMNAHPGDKMT2A | |
| SCHEMBL3180834 | 0.64 | SLC22A12 (0.47) | SLC22A12ALDH1A1GAALMNAHPGD | |
| SCHEMBL27583476 | 0.64 | PDE10A (0.60) | ALDH1A1LMNAKMT2ASMN1; SMN2TSHR | |
| SCHEMBL20916899 | 0.63 | TDP1 (0.47) | SLC22A12ALDH1A1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |