Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615184 | 0.86 | SLC22A12 (0.45) | SLC22A12ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL11464795 | 0.73 | NPBWR1 (0.41) | SLC22A12ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL11611744 | 0.72 | GRN (0.43) | ALDH1A1LMNAHPGDMAPTKMT2A | |
| SCHEMBL11508658 | 0.71 | MAPT (0.45) | SLC22A12LMNAHPGDMAPTKMT2A | |
| SCHEMBL11613140 | 0.69 | SMN1; SMN2 (0.44) | ALDH1A1LMNAHPGDMAPTTSHR | |
| SCHEMBL11612470 | 0.69 | MTNR1A (0.44) | ALDH1A1LMNAHPGDMAPTTP53 | |
| SCHEMBL3177634 | 0.68 | SLC22A12 (0.54) | SLC22A12MAPTTDP1 | |
| SCHEMBL18512515 | 0.68 | SLC22A12 (0.64) | SLC22A12ALDH1A1LMNAHPGD | |
| SCHEMBL11977216 | 0.68 | SLC22A12 (1.00) | SLC22A12ALDH1A1HPGDTDP1 | |
| SCHEMBL3180834 | 0.68 | SLC22A12 (0.47) | SLC22A12ALDH1A1LMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |