Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicine SCHEMBL30898941 | 0.85 | KDM4E (0.43) | TDP1KDM4EALOX15BLMPMP22 | |
| Bicine SCHEMBL22401348 | 0.79 | ALOX15 (0.59) | TDP1KDM4EALOX15BLMPMP22 | |
| SCHEMBL267577 | 0.79 | — | — | |
| SCHEMBL186529 | 0.79 | — | — | |
| SCHEMBL11745103 | 0.77 | CHRM1 (0.35) | TDP1ADRA1ADRD3SLC6A3 | |
| Potassium SCHEMBL30898938 | 0.77 | CA2 (0.39) | TDP1TSHRADRA1ADRD3SLC6A3 | |
| SCHEMBL31260158 | 0.77 | CHRM1 (0.35) | TDP1ADRA1ADRD3SLC6A3MAPT | |
| Bicine SCHEMBL177696 | 0.77 | ALOX15 (0.68) | TDP1KDM4EALOX15BLMPMP22 | |
| Bicine SCHEMBL34161 | 0.77 | ALOX15 (0.68) | TDP1KDM4EALOX15BLMPMP22 | |
| SCHEMBL5177311 | 0.77 | TDP1 (0.33) | TDP1KDM4EALOX15BLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350649-A1 | STABLE ANTIBODY COMPOSITIONS AND METHODS FOR STABILIZING SAME | Abbott Laboratories (US) | 2011-08-03 | — | — | EP | claimed |
| EP-1482912-B1 | NALTREXONE HYDROCHLORIDE COMPOSITIONS | EURO CELTIQUE SA (LU) | 2011-05-25 | — | — | EP | claimed |
| JP-4683842-B2 | — | — | 2011-05-18 | — | — | JP | claimed |
| US-20240368284-A1 | A METHOD OF IMPROVING STABILITY OF IMMUNE CHECK POINT INHIBITORS | DR. REDDY'S LABORATORIES LIMITED (IN) | 2024-11-07 | — | — | US | disclosed |
| US-20140249172-A1 | INTRANASAL NALTREXONE | 3B PHARMACEUTICALS, INC. (US) | 2014-09-04 | — | — | US | disclosed |
| US-20110206680-A1 | METHODS FOR TREATING PSORIASIS | ABBOTT LABORATORIES (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2350649-A1 | STABLE ANTIBODY COMPOSITIONS AND METHODS FOR STABILIZING SAME | Abbott Laboratories (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20110171217-A1 | STABLE LIQUID ANTIBODY FORMULATION | PFIZER INC | 2011-07-14 | — | — | US | disclosed |
| EP-1482912-B1 | NALTREXONE HYDROCHLORIDE COMPOSITIONS | EURO CELTIQUE SA (LU) | 2011-05-25 | — | — | EP | disclosed |
| EP-2311491-A1 | Composition comprising an antibody against macrophage colony-stimulating factor (M-CSF) and a chelating agent | Pharmacia & Upjohn Company LLC (US) | 2011-04-20 | — | — | EP | disclosed |
| EP-2289492-A2 | Naltrexone hydrochloride compositions | EURO-CELTIQUE S.A. (LU) | 2011-03-02 | — | — | EP | disclosed |
| WO-2011015634-A2 | CONTROLLED RELEASE FORMULATIONS OF LIPOCALIN MUTEINS | PIERIS AG (DE) | 2011-02-10 | — | — | WO | disclosed |
| US-20110027262-A1 | PLATFORM ANTIBODY COMPOSITIONS | PHARMACIA & UPJOHN COMPANY LLC | 2011-02-03 | — | — | US | disclosed |