Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 15/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | NQO2 | P16083 | 4/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822777 | 0.88 | MTNR1A (0.79) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7891030 | 0.86 | MTNR1A (0.76) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7894816 | 0.86 | MTNR1A (0.80) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18239788 | 0.86 | MTNR1A (0.75) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16716178 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8822712 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15428065 | 0.84 | MTNR1A (0.72) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15427771 | 0.83 | MTNR1A (0.71) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL677575 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7883115 | 0.80 | MTNR1A (0.80) | MTNR1AMTNR1BCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1047936-C | Method for producing pharmaceutical composite containing alkylmelatonins | LILLY CO ELI (US) | 2000-01-05 | — | — | CN | disclosed |
| CN-1064807-A | Preparation contains the method for the pharmaceutical composition of Alkylmelatonins | LILLY CO ELI (US) | 1992-09-30 | — | — | CN | disclosed |
| CN-1017426-B | Process for preparing alkyl melatonin | LILLY CO ELI (US) | 1992-07-15 | — | — | CN | disclosed |
| CN-88100478-A | alkyl melatonin | — | 1988-08-17 | — | — | CN | disclosed |
| US-4087444-A | Amides as ovulation inhibitors | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |