Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 14/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883115 | 0.89 | MTNR1A (0.80) | MTNR1AMTNR1BHSD17B10TP53NQO2 | |
| SCHEMBL7883051 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1BHSD17B10KDM4E | |
| SCHEMBL7888564 | 0.84 | MTNR1A (0.72) | MTNR1AMTNR1BHSD17B10TP53NQO2 | |
| SCHEMBL11615487 | 0.83 | MTNR1A (1.00) | MTNR1AMTNR1BHSD17B10TP53NQO2 | |
| SCHEMBL8822711 | 0.81 | MTNR1A (0.66) | MTNR1AMTNR1BHSD17B10NQO2CYP1A2 | |
| SCHEMBL7893103 | 0.79 | MTNR1A (0.69) | MTNR1AMTNR1BHSD17B10NQO2CYP1A2 | |
| SCHEMBL10908623 | 0.79 | MTNR1A (0.64) | MTNR1AMTNR1BHSD17B10TP53CYP1A2 | |
| SCHEMBL18239788 | 0.78 | MTNR1A (0.75) | MTNR1AMTNR1BHSD17B10NQO2CYP1A2 | |
| SCHEMBL7894816 | 0.78 | MTNR1A (0.80) | MTNR1AMTNR1BHSD17B10TP53NQO2 | |
| SCHEMBL8822717 | 0.75 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056897-B1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES B V (NL) | 2009-12-30 | — | — | EP | claimed |
| US-20090258053-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEEVICES BV (NL) | 2009-10-15 | — | — | US | claimed |
| EP-2056897-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | Blue Medical Devices B.V. (NL) | 2009-05-13 | — | — | EP | claimed |
| WO-2008023038-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | WO | claimed |
| EP-4706758-A2 | METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20240325487-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2024-10-03 | — | — | US | disclosed |
| US-11813304-B2 | Compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230277523-A1 | METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| EP-3884935-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-114404588-A | Compounds and methods for inhibiting phosphate transport | 阿德利克斯公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114340631-A | Combination for reducing serum phosphate in a patient | 阿德利克斯股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-3972599-A1 | COMBINATION FOR LOWERING SERUM PHOSPHATE IN A PATIENT | Ardelyx, Inc. (US) | 2022-03-30 | — | — | EP | disclosed |
| US-6239162-B1 | ADMINISTERING 5-METHOXYCARBONYLAMINO-N-ACETYLTRYPTAMINE; ANXIOLYTIC AGENTS; OBSESSIVE COMPULSIVE DISORDER | ST. ELIZABETH'S MEDICAL CENTER | 2001-05-29 | — | — | US | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5151446-A | Neurological disorders or cardiovascular disorders | NORTHWESTERN UNIVERSITY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5071875-A | Nervous system, psychological disorders; sleep cycle, skin dis coloration | NORTHWESTERN UNIVERSITY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0420064-A2 | Substituted 2-amidotetralins as melatonin agonists and antagonists | NORTHWESTERN UNIVERSITY (US) | 1991-04-03 | — | — | EP | disclosed |
| EP-0375726-A4 | MELATONIN ANALOGUES | — | 1991-01-30 | — | — | EP | disclosed |
| EP-0375726-A1 | MELATONIN ANALOGUES | Whitby Research Incorporated (US) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989001472-A1 | MELATONIN ANALOGUES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258053-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | MTNR1B, MTNR1A, MYLK | MTNR1A 2/4885MTNR1B 1/4885HSD17B10 3987/4885 |
| US-20240325487-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A3, SLC34A2, SLC34A1 | MTNR1A 3262/4885MTNR1B 3128/4885HSD17B10 1801/4885 |
| US-11813304-B2 | Compounds and methods for inhibiting phosphate transport | SLC34A3, SLC34A2, SLC34A1 | MTNR1A 3262/4885MTNR1B 3128/4885HSD17B10 1801/4885 |
| US-20230277523-A1 | METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A3, SLC34A2, SLC34A1 | MTNR1A 3825/4885MTNR1B 3664/4885HSD17B10 1990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.