Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613363 | 0.86 | NPSR1 (0.58) | NPSR1LMNAATMPKMSMN1; SMN2 | |
| SCHEMBL11610956 | 0.86 | LMNA (0.58) | NPSR1LMNAATMPKMSMN1; SMN2 | |
| SCHEMBL11612850 | 0.81 | NPSR1 (0.74) | NPSR1LMNAATMPKMSMN1; SMN2 | |
| SCHEMBL20335020 | 0.81 | NPSR1 (0.74) | NPSR1LMNAATMSMN1; SMN2MAPK1 | |
| SCHEMBL6380632 | 0.81 | NPSR1 (0.74) | NPSR1LMNAATMSMN1; SMN2MAPK1 | |
| SCHEMBL11617093 | 0.81 | LMNA (0.79) | NPSR1LMNAATMSMN1; SMN2MAPK1 | |
| SCHEMBL6375965 | 0.80 | LMNA (0.67) | NPSR1LMNAATMSMN1; SMN2MAPK1 | |
| SCHEMBL8744796 | 0.79 | LMNA (0.58) | NPSR1LMNAATMPKMSMN1; SMN2 | |
| SCHEMBL8744787 | 0.79 | LMNA (0.58) | NPSR1LMNAATMPKMSMN1; SMN2 | |
| SCHEMBL11614967 | 0.79 | LMNA (0.59) | NPSR1LMNAATMPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093444-A | Hydantoin derivatives and methods for regulating plant-growth | PEPRO, SOCIETE POUR LE DEVELOPPEMENT ET LA VENTE DE SPECIALITES CHIMIQUES (FR) | 1978-06-06 | — | — | US | disclosed |
| US-3990883-A | N-(1-carboxy-3-methylthio)propyl urea derivatives and compositions having plant-growth regulating properties | PEPRO, SOCIETE POUR LE DEVELOPEMENT ET AL VENTE DE SPECIALITIES CHIMIQUES (FR) | 1976-11-09 | — | — | US | disclosed |