Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615687 | 1.00 | PPARG (0.49) | PPARGPPARANPC1RAB9ACCR8 | |
| SCHEMBL7832912 | 0.89 | PPARG (0.46) | PPARGPPARANPC1RAB9ACCR8 | |
| SCHEMBL29626835 | 0.89 | PPARG (0.46) | PPARGPPARANPC1RAB9ACCR8 | |
| SCHEMBL11573521 | 0.82 | NPC1 (0.50) | PPARGPPARANPC1RAB9ACCR8 | |
| SCHEMBL11573519 | 0.82 | NPC1 (0.50) | PPARGPPARANPC1RAB9ACCR8 | |
| SCHEMBL27369629 | 0.77 | L3MBTL1 (0.47) | PPARGPPARANPC1RAB9AALDH1A1 | |
| SCHEMBL11056588 | 0.72 | CD274 (0.46) | — | |
| SCHEMBL11056547 | 0.72 | CD274 (0.46) | — | |
| SCHEMBL11451678 | 0.71 | FFAR1 (0.46) | CETPALDH1A1MAPTL3MBTL1FFAR4 | |
| SCHEMBL9558288 | 0.71 | PPARG (0.46) | PPARGPPARACCR8KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108897-A | Benzylhydroxylamine ethers | SHELL OIL COMPANY (US) | 1978-08-22 | — | — | US | disclosed |