Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147075 | 0.80 | MAPT (0.45) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL8915316 | 0.80 | PPARG (0.41) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL14627769 | 0.79 | MAPT (0.48) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL22548068 | 0.77 | ALDH1A1 (0.43) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL13510803 | 0.77 | ALDH1A1 (0.43) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL19733323 | 0.77 | L3MBTL1 (0.71) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL4451421 | 0.77 | L3MBTL1 (0.71) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL11615686 | 0.77 | PPARG (0.49) | L3MBTL1NPC1RAB9APPARGPPARA | |
| SCHEMBL2051105 | 0.76 | NPC1 (0.49) | L3MBTL1NPC1RAB9ASMN1; SMN2PPARG | |
| SCHEMBL22672464 | 0.76 | POLB (0.44) | L3MBTL1RAB9ASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |