Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | MPI | P34949 | 1/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | DDO | Q99489 | 1/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25419480 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL11619027 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL11619748 | 0.76 | AHR (0.49) | KDM4EMAPTDAODDOHPGD | |
| SCHEMBL1884123 | 0.76 | KDM4E (1.00) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL2726546 | 0.75 | DAO (0.73) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL29505902 | 0.75 | DAO (0.73) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL30875869 | 0.74 | MAPT (0.58) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6202865 | 0.73 | AHR (0.55) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL2943656 | 0.72 | KDM4E (0.65) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL3360017 | 0.72 | DAO (1.00) | KDM4EALDH1A1MAPTIDEMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127574-A | ANTIALLERGENS | SANDOZ, INC. (US) | 1978-11-28 | — | — | US | disclosed |