Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.55 |
| ▸ | PDE9A | O76083 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132803 | 0.78 | MAPT (0.71) | MAPTPDE9AESR1ESR2KDM4E | |
| SCHEMBL378030 | 0.77 | MAPT (0.65) | MAPTPDE9AESR1ESR2KDM4E | |
| SCHEMBL10648743 | 0.76 | MAPT (0.59) | MAPTPDE9AESR1ESR2KDM4E | |
| SCHEMBL24095618 | 0.75 | CSF1R (0.64) | MAPTPTGS2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL19952766 | 0.75 | PTGS2 (0.62) | PTGS2KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL6202865 | 0.74 | AHR (0.55) | MAPTPTGS2KDM4EALDH1A1MEN1 | |
| SCHEMBL11617005 | 0.74 | KDM4E (0.61) | MAPTKDM4EALDH1A1MEN1TNKS | |
| SCHEMBL8987076 | 0.73 | MAPT (0.60) | MAPTPTGS2PDE9AESR1ESR2 | |
| SCHEMBL6825380 | 0.73 | MAPT (0.65) | MAPTPDE9AESR1ESR2KDM4E | |
| SCHEMBL1239816 | 0.73 | MAPT (0.65) | MAPTPDE9AESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710223-B | Preparation method of 3-aryl quinolinone derivative | 广东工业大学 | 2024-05-10 | — | — | CN | disclosed |