Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615587 | 0.87 | TDP1 (0.49) | KMT2AMEN1RAB9AMAPK1TDP1 | |
| SCHEMBL11612391 | 0.86 | RAB9A (0.46) | KMT2AMEN1RAB9AMAPK1TDP1 | |
| SCHEMBL11615627 | 0.85 | TDP1 (0.50) | KMT2AMEN1RAB9AMAPK1TDP1 | |
| SCHEMBL11615840 | 0.84 | TDP1 (0.48) | KMT2AMEN1RAB9AMAPK1TDP1 | |
| SCHEMBL11616914 | 0.82 | TDP1 (0.44) | KMT2AMEN1RAB9AMAPK1TDP1 | |
| SCHEMBL11612294 | 0.77 | RAB9A (0.48) | KMT2AMEN1RAB9AMAPK1TDP1 | |
| SCHEMBL3310123 | 0.74 | MEN1 (0.52) | KMT2AMEN1ESR1ATMESR2 | |
| SCHEMBL11615774 | 0.73 | KMT2A (0.53) | KMT2AMEN1RAB9ATDP1GAA | |
| SCHEMBL11616709 | 0.72 | NPC1 (0.50) | KMT2AMEN1RAB9AMAPK1TDP1 | |
| SCHEMBL11613986 | 0.72 | KMT2A (0.53) | KMT2AMEN1RAB9ATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |