⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461154 | 1.00 | — | — | |
| SCHEMBL13039799 | 1.00 | — | — | |
| SCHEMBL11597748 | 0.81 | AKT1 (0.50) | — | |
| SCHEMBL41825 | 0.79 | — | — | |
| SCHEMBL41826 | 0.79 | — | — | |
| SCHEMBL18131527 | 0.79 | — | — | |
| SCHEMBL22660275 | 0.79 | — | — | |
| SCHEMBL15750770 | 0.79 | — | — | |
| SCHEMBL25276069 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL2835611 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669137-B2 | Modified polylactide polymers | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20150217028-A1 | MODIFIED PLA POLYMER AND METHOD OF MAKING AND USING | ABBOTT CARDIOVASCULAR SYSTEMS INC. | 2015-08-06 | — | — | US | disclosed |
| EP-2461683-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | Biogen Idec MA Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017561-A1 | BICYCLIC ARYL SPHINGOSINE 1-PHOSPHATE ANALOGS | BIOGEN IDEC MA INC. (US) | 2011-02-10 | — | — | WO | disclosed |
| US-5004568-A | Reacting With Carbon Monoxide Using A Group 8 Noble Metal Halide Catalyst And A Group 1B Metal Halide | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4767574-A | CATALYTIC WITH GROUP 8 NOBLE METAL HALIDE AND HALIDE COMPOUND | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4675435-A | CARBONYLATION OF ACYCLIC ALLYLIC ETHER | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0217407-A2 | Carbonylation of allylic ethers to esters | QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4622416-A | GROUP 8 HALIDE CATALYSTS | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1986-11-11 | — | — | US | disclosed |