SCHEMBL461154

SCHEMBL461154

COC/C=C/C(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1161835 1.00
SCHEMBL13039799 1.00
SCHEMBL11597748 0.81 AKT1 (0.50)
SCHEMBL41825 0.79
SCHEMBL41826 0.79
SCHEMBL18131527 0.79
SCHEMBL22660275 0.79
SCHEMBL15750770 0.79
SCHEMBL25276069 0.77 ALDH1A1 (0.42)
SCHEMBL2835611 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4685907-A1 ELECTROLYTE, SECONDARY BATTERY AND ELECTRICAL APPARATUS Contemporary Amperex Technology Co., Limited (CN) 2026-01-28 EP disclosed
US-20250385311-A1 ELECTROLYTIC SOLUTION, SECONDARY BATTERY AND ELECTRIC DEVICE CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2025-12-18 US disclosed
WO-2025065868-A1 ELECTROLYTE, SECONDARY BATTERY AND ELECTRICAL APPARATUS 宁德时代新能源科技股份有限公司 2025-04-03 WO disclosed
CN-119725719-A Electrolyte, secondary battery and electricity utilization device 宁德时代新能源科技股份有限公司 2025-03-28 CN disclosed
US-20230293532-A1 USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) PHARMACYCLICS LLC (US) 2023-09-21 US disclosed
US-20230293532-A1 USE OF INHIBITORS OF BRUTONS TYROSINE KINASE (BTK) PHARMACYCLICS LLC (US) 2023-09-21 US disclosed
US-20170362246-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE PHARMACYCLICS LLC 2017-12-21 US disclosed
US-9844552-B2 Methods of treating fibrosis PHARMACYCLICS LLC (US) 2017-12-19 US disclosed
US-20170354655-A1 TLR INHIBITOR AND BRUTON'S TYROSINE KINASE INHIBITOR COMBINATIONS PHARMACYCLICS LLC 2017-12-14 US disclosed
US-9801883-B2 Use of inhibitors of bruton's tyrosine kinase (Btk) PHARMACYCLICS LLC (US) 2017-10-31 US disclosed
US-20100004270-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE PHARMACYCLICS, INC. (US) 2010-01-07 US disclosed
US-7514444-B2 Inhibitors of bruton's tyrosine kinase PHARMACYCLICS, INC. (US) 2009-04-07 US disclosed
WO-2008121742-A2 INHIBITORS OF BRUTON'S TYROSINE KINASE PHARMACYCLICS, INC. (US) 2008-10-09 WO disclosed
US-20080139582-A1 4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidine derivatives; can be covalently bonded to Bruton's tyrosine kinase; autoimmune diseases, lymphoma, leukemia; antiproliferative, anticarcinogenic and antiinflammatory agents PHARMACYCLICS, INC. (US) 2008-06-12 US disclosed
US-20080108636-A1 compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are told PHARMACYCLICS, INC. (US) 2008-05-08 US disclosed
US-5004568-A Reacting With Carbon Monoxide Using A Group 8 Noble Metal Halide Catalyst And A Group 1B Metal Halide NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1991-04-02 US disclosed
US-4767574-A CATALYTIC WITH GROUP 8 NOBLE METAL HALIDE AND HALIDE COMPOUND NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1988-08-30 US disclosed
US-4675435-A CARBONYLATION OF ACYCLIC ALLYLIC ETHER NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1987-06-23 US disclosed
EP-0217407-A2 Carbonylation of allylic ethers to esters QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1987-04-08 EP disclosed
US-4622416-A GROUP 8 HALIDE CATALYSTS NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1986-11-11 US disclosed