Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525000 | 0.84 | KMT2A (0.61) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL10889755 | 0.84 | KMT2A (0.69) | KMT2AAPEX1LMNAMAPTKDM4E | |
| Calcium SCHEMBL31224591 | 0.83 | KMT2A (0.59) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL11616885 | 0.83 | KMT2A (0.59) | KMT2AAPEX1LMNAMAPTHDAC7 | |
| SCHEMBL11115291 | 0.82 | ALDH1A1 (0.56) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL6385721 | 0.81 | HDAC6 (0.76) | LMNAHDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL9695573 | 0.79 | HTT (0.63) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL5849754 | 0.79 | HTT (0.63) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL8655179 | 0.79 | KMT2A (0.54) | KMT2AAPEX1LMNAMAPTKDM4E | |
| SCHEMBL11416343 | 0.78 | KMT2A (0.59) | KMT2AAPEX1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077998-A | Phthaloyl amino acid hydroxamic acids | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-03-07 | — | — | US | claimed |
| US-4099010-A | PHTHALOYL AMINO ACID HYDROXAMIC ACIDS | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4077998-A | Phthaloyl amino acid hydroxamic acids | MORTON-NORWICH PRODUCTS, INC. (US) | 1978-03-07 | — | — | US | disclosed |