SCHEMBL5849754

SCHEMBL5849754

O=C(O)c1ccccc1C(=O)NCCO

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.63
KMT2A Q03164 3/20 0.62
APEX1 P27695 1/20 0.62
MAPT P10636 2/20 0.59
LMNA P02545 1/20 0.59
ALDH1A1 P00352 4/20 0.56
KDM4E B2RXH2 2/20 0.56
TAAR1 Q96RJ0 1/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
TSHR P16473 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALOX15 P16050 1/20 0.54
MEN1 O00255 1/20 0.54
CACNA1B Q00975 1/20 0.54
APBA1 Q02410 1/20 0.54
MAPK1 P28482 1/20 0.53
USP2 O75604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9695573 1.00 HTT (0.63) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL8894839 0.92 ALDH1A1 (0.62) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL10889755 0.90 KMT2A (0.69) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL23773211 0.85 HTT (0.55) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL15796793 0.84 KMT2A (0.67) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL1246548 0.84 AKR1C3 (0.53) HTTKMT2AMAPTALDH1A1KDM4E
SCHEMBL10158103 0.83 HTT (0.68) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL9570919 0.83 ALDH1A1 (0.54) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL30525000 0.83 KMT2A (0.61) HTTKMT2AAPEX1MAPTLMNA
SCHEMBL7150327 0.83 KMT2A (0.61) HTTKMT2AAPEX1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7141614-B2 Photosensitive resin composition and photosensitive films and laminates made by using the same KANEKA CORPORATION (JP) 2006-11-28 US disclosed
US-20040265731-A1 Photosensitive resin composition and photosensitive films and laminates made by using the same KANEKA CORPORATION (JP) 2004-12-30 US disclosed