Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13442860 | 0.94 | CASP3 (0.70) | UBE2NTDP1KMT2ACASP3CA2 | |
| SCHEMBL28737148 | 0.87 | UBE2N (0.82) | UBE2NTDP1CA2CA9CA12 | |
| SCHEMBL2258501 | 0.87 | KMT2A (0.70) | KMT2ACASP3CA2CA9CA12 | |
| SCHEMBL18669018 | 0.86 | CASP3 (0.63) | UBE2NTDP1KMT2ACASP3CA2 | |
| SCHEMBL7954623 | 0.83 | CASP3 (0.59) | UBE2NTDP1CASP3CA2CA9 | |
| SCHEMBL18974298 | 0.83 | ALDH1A1 (0.73) | UBE2NTDP1KMT2ACASP3CA2 | |
| SCHEMBL14303138 | 0.83 | UBE2N (0.63) | UBE2NTDP1KMT2ACA2CA9 | |
| SCHEMBL15437827 | 0.82 | NR1H2 (0.52) | UBE2NTDP1KMT2ACA2CA9 | |
| SCHEMBL31430155 | 0.81 | KMT2A (0.63) | KMT2ACASP3CA12NPSR1MEN1 | |
| SCHEMBL5010655 | 0.81 | KMT2A (0.75) | UBE2NTDP1KMT2ACA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124375-A | Substituted phthalimides for regulating the growth of plants | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | claimed |
| WO-2017049409-A1 | COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME | THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017049409-A1 | COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME | THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2017-03-30 | — | — | WO | disclosed |