Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336655 | 0.82 | ABCG2 (0.48) | ABCG2ABCC1ABCB1SNCACA12 | |
| SCHEMBL16392095 | 0.73 | ABCG2 (0.54) | ABCG2ABCC1ABCB1MEN1KMT2A | |
| SCHEMBL17800986 | 0.71 | ABCG2 (0.53) | ABCG2ABCC1ABCB1MEN1KMT2A | |
| SCHEMBL16391872 | 0.71 | PTGS2 (0.58) | ABCG2ABCC1ABCB1MEN1KMT2A | |
| SCHEMBL6865288 | 0.71 | SNCA (0.72) | MEN1KMT2ASNCACA12CA1 | |
| SCHEMBL11685681 | 0.71 | ROCK1 (0.57) | SNCACA12CA1CA2CA9 | |
| SCHEMBL16391710 | 0.70 | ABCG2 (0.56) | ABCG2ABCC1ABCB1MEN1KMT2A | |
| SCHEMBL18421634 | 0.70 | SNCA (0.62) | MEN1KMT2ASNCACA12CA1 | |
| SCHEMBL16391720 | 0.70 | ABCG2 (0.55) | ABCG2ABCC1ABCB1MEN1KMT2A | |
| SCHEMBL11615841 | 0.69 | KMT2A (0.81) | MEN1KMT2ACYP1A2CYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4084053-A | YELLOW AND ORANGE DYES, PYRIMIDINO(4',5':5,6)-1,2,4-TRIAZINO(4,3-BETA)INDAZOLES | CIBA-GEIGY CORPORATION (US) | 1978-04-11 | — | — | US | disclosed |