Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | XBP1 | P17861 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220354 | 0.75 | HPGD (0.37) | ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL86410 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL922881 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL1416929 | 0.73 | MAPT (0.52) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL11466845 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL212550 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL921425 | 0.65 | ALDH1A1 (0.42) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL77082 | 0.65 | ALDH1A1 (0.50) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL11619001 | 0.63 | MCL1 (0.43) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL1416827 | 0.63 | ALDH1A1 (1.00) | ALDH1A1MAPTXBP1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098598-A | PLANT GROWTH REGULATORS | HOFFMANN-LA ROCHE INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4028089-A | BENZOXAZOLINYLIDENE-MALONITRILE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1977-06-07 | — | — | US | disclosed |