Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | XBP1 | P17861 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212550 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL12220353 | 0.78 | CTSK (0.33) | CTSKCTSS | |
| SCHEMBL20694705 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MAPTRAB9ANPC1HPGD | |
| SCHEMBL77082 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL3192961 | 0.70 | CTSK (0.33) | CTSKCTSS | |
| SCHEMBL3192956 | 0.70 | CTSK (0.33) | CTSKCTSS | |
| SCHEMBL922881 | 0.70 | ALDH1A1 (0.55) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL86410 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTXBP1MAPK1RAB9A | |
| SCHEMBL31484126 | 0.69 | ALDH1A1 (0.42) | ALDH1A1MAPTRAB9ALMNAPKM | |
| SCHEMBL1416929 | 0.69 | MAPT (0.52) | ALDH1A1MAPTXBP1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573074-B1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2014-07-23 | — | — | EP | disclosed |
| EP-2573074-B1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8598085-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | disclosed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2573074-A1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | Dow AgroSciences LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| EP-2573074-A1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | Dow AgroSciences LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | disclosed |
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | disclosed |
| EP-2264034-A1 | BICYCLIC PYRROLE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2176239-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009023438-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009023438-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | US | disclosed |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | US | disclosed |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | ALDH1A1 314/4885MAPT 2800/4885XBP1 4224/4885 |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | ALDH1A1 348/4885MAPT 2783/4885XBP1 4219/4885 |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | ALDH1A1 314/4885MAPT 2800/4885XBP1 4224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.