Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520417 | 0.84 | MEN1 (0.49) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL11522239 | 0.81 | MEN1 (0.43) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL10555024 | 0.77 | APEX1 (0.57) | APEX1BLMMEN1KMT2ASIGMAR1 | |
| SCHEMBL11620380 | 0.74 | APEX1 (0.60) | APEX1BLMSIGMAR1TSHRPOLB | |
| SCHEMBL563022 | 0.73 | TP53 (0.67) | APEX1BLMMEN1KMT2ASIGMAR1 | |
| SCHEMBL1906215 | 0.73 | TP53 (0.67) | APEX1BLMMEN1KMT2ASIGMAR1 | |
| SCHEMBL3155232 | 0.73 | TP53 (0.67) | APEX1BLMMEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL32688148 | 0.72 | TP53 (0.65) | APEX1BLMMEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL32688158 | 0.72 | TP53 (0.65) | APEX1BLMMEN1KMT2ASIGMAR1 | |
| SCHEMBL11523044 | 0.71 | MEN1 (0.47) | MEN1KMT2ACHRNA7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118396-A | PYRROLIDIN-2-ONES, CNS AGENTS | I.S.F. S.P.A. (IT) | 1978-10-03 | — | — | US | claimed |
| US-4118396-A | PYRROLIDIN-2-ONES, CNS AGENTS | I.S.F. S.P.A. (IT) | 1978-10-03 | — | — | US | disclosed |