Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520417 | 0.83 | MEN1 (0.49) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL692642 | 0.82 | HSD17B10 (0.37) | MEN1KMT2AHSD17B10TSHRUSP2 | |
| SCHEMBL11620131 | 0.81 | APEX1 (0.49) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL8750285 | 0.75 | KCNA3 (0.32) | MEN1KMT2AHSD17B10TSHRUSP2 | |
| SCHEMBL11124160 | 0.73 | CHRNB2 (0.49) | MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL11073331 | 0.73 | MEN1 (0.40) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL10760741 | 0.71 | TSHR (0.63) | MEN1KMT2AHSD17B10TSHRUSP2 | |
| SCHEMBL11523044 | 0.70 | MEN1 (0.47) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL11667674 | 0.70 | MEN1 (0.44) | MEN1KMT2ACHRNA7HTR3EHTR3B | |
| SCHEMBL15193256 | 0.69 | CHRNA7 (0.56) | MEN1KMT2ACHRNA7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4173569-A | Preparation of pyrrolidine and pyrrolidin-2-one derivatives | I.S.F. SPA (IT) | 1979-11-06 | — | — | US | disclosed |