Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906215 | 1.00 | TP53 (0.67) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL563022 | 1.00 | TP53 (0.67) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL32688158 | 0.98 | TP53 (0.65) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL32688148 | 0.98 | TP53 (0.65) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9850874 | 0.88 | TP53 (0.70) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9821188 | 0.85 | TP53 (0.67) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL32688308 | 0.84 | TP53 (0.74) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL20573309 | 0.84 | TP53 (0.74) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL32688612 | 0.83 | TP53 (0.72) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11553488 | 0.81 | LMNA (0.71) | TP53TSHRHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160250185-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-09-01 | — | — | US | claimed |
| US-11465135-B2 | Bifunctional chiral organocatalytic compound having excellent enantioselectivity, preparation method therefor, and method for producing non-natural gamma-amino acid from nitro compound by using same | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2022-10-11 | — | — | US | disclosed |
| US-20200406243-A1 | BIFUNCTIONAL CHIRAL ORGANOCATALYTIC COMPOUND HAVING EXCELLENT ENANTIOSELECTIVITY, PREPARATION METHOD THEREFOR, AND METHOD FOR PRODUCING NON-NATURAL GAMMA-AMINO ACID FROM NITRO COMPOUND BY USING SAME | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2020-12-31 | — | — | US | disclosed |
| US-20200406243-A1 | BIFUNCTIONAL CHIRAL ORGANOCATALYTIC COMPOUND HAVING EXCELLENT ENANTIOSELECTIVITY, PREPARATION METHOD THEREFOR, AND METHOD FOR PRODUCING NON-NATURAL GAMMA-AMINO ACID FROM NITRO COMPOUND BY USING SAME | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2020-12-31 | — | — | US | disclosed |
| EP-3142662-B1 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH ELEVATED INDUCIBLE NITRIC OXIDE SYNTHASE | AKCIJU SABIEDRIBA OLAINFARM (LV) | 2020-07-08 | — | — | EP | disclosed |
| US-20180064687-A1 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH ELEVATED INDUCIBLE NITRIC OXIDE SYNTHASE | AKCIJU SABIEDRIBA "OLAINFARM" (LV) | 2018-03-08 | — | — | US | disclosed |
| US-20160250185-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-09-01 | — | — | US | disclosed |
| US-20160250185-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-09-01 | — | — | US | disclosed |
| WO-2015060702-A8 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-07-07 | — | — | WO | disclosed |
| US-9382203-B2 | N-carbamoylmethyl-4-(R)-phenyl-2-pyrrolidinone, method of its preparation and pharmaceutical use | Joint Stock Company (JSC) “OLAINFARM” (LV) | 2016-07-05 | — | — | US | disclosed |
| US-20150216846-A1 | N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use | JOINT STOCK COMPANY (JSC) "OLAINFARM" (LV) | 2015-08-06 | — | — | US | disclosed |
| WO-2015060702-A1 | PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2015-04-30 | — | — | WO | disclosed |
| US-20140315972-A1 | RS)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide compound having modulatory activity with a commensurate effect, pharmaceutical substance (variants) and its application, composition (variants) thereof | AKHAPKINA, VALENTINA IVANOVNA (RU) | 2014-10-23 | — | — | US | disclosed |
| CN-103987386-A | (RS) -2- (2-oxo-4-phenylpyrrolidin-1-yl) acetamide compounds with modulating activity with commensurate effects, pharmaceutical substances (variants) and uses thereof, compositions (variants) thereof | AKHAPKINA VALENTINA IVANOVNA | 2014-08-13 | — | — | CN | disclosed |
| EP-2762138-A1 | PHARMACEUTICAL SUBSTANCE (VARIANTS) AND COMPOSITIONS BASED THEREON WHICH EXHIBIT MODULATORY ACTIVITY WITH A COMMENSURATE EFFECT | Akhapkina, Valentina Ivanovna (RU) | 2014-08-06 | — | — | EP | disclosed |
| EP-2013166-B1 | N-CARBAMOYLMETHYL-4(R)-PHENYL-2-PYRROLIDINONE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL USE | AKCIJU SABIEDRIBA OLAINFARM (LV) | 2010-03-10 | — | — | EP | disclosed |
| US-20100022784-A1 | N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use | Joint Stock Company "Olainfarm" (LV) | 2010-01-28 | — | — | US | disclosed |
| US-20100022784-A1 | N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use | Joint Stock Company "Olainfarm" (LV) | 2010-01-28 | — | — | US | disclosed |
| EP-2013166-A2 | N-CARBAMOYLMETHYL-4(R)-PHENYL-2-PYRROLIDINONE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL USE | Akciju Sabiedriba "Olainfarm" (LV) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007104780-A2 | N- CARBAMOYLMETHYL- 4- (R) -PHENYL-2-PYRR0LIDIN0NE, METHOD OF ITS PREPARATION AND PHARMACEUTICAL USE | AKCIJU SABIEDRIBA 'OLAINFARM' (LV) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465135-B2 | Bifunctional chiral organocatalytic compound having excellent enantioselectivity, preparation method therefor, and method for producing non-natural gamma-amino acid from nitro compound by using same | NOTUM, ALDH7A1, AADAT | TP53 3270/4885TSHR 4266/4885HPGD 863/4885 |
| US-20100022784-A1 | N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use | PRMT6, CPS1, JMJD6 | TP53 3584/4885TSHR 1892/4885HPGD 1201/4885 |
| US-20200406243-A1 | BIFUNCTIONAL CHIRAL ORGANOCATALYTIC COMPOUND HAVING EXCELLENT ENANTIOSELECTIVITY, PREPARATION METHOD THEREFOR, AND METHOD FOR PRODUCING NON-NATURAL GAMMA-AMINO ACID FROM NITRO COMPOUND BY USING SAME | NOTUM, ALDH7A1, AADAT | TP53 3270/4885TSHR 4266/4885HPGD 863/4885 |
| US-20180064687-A1 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH ELEVATED INDUCIBLE NITRIC OXIDE SYNTHASE | ARG2, NOS2, NOS3 | TP53 2065/4885TSHR 3378/4885HPGD 155/4885 |
| US-20150216846-A1 | N-Carbamoylmethyl-4-(R)-Phenyl-2-Pyrrolidinone, Method of its Preparation and Pharmaceutical Use | PRMT6, CPS1, JMJD6 | TP53 3584/4885TSHR 1892/4885HPGD 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.