Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618875 | 0.99 | RAB9A (0.58) | RAB9ANPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL11618263 | 0.83 | KDM4E (0.49) | RAB9AKDM4EALDH1A1TP53ALOX15 | |
| SCHEMBL11616315 | 0.82 | KDM4E (0.51) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL11616547 | 0.81 | KDM4E (0.45) | RAB9AKDM4EALDH1A1MEN1POLB | |
| SCHEMBL11620424 | 0.80 | KDM4E (0.47) | RAB9ANPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL11617455 | 0.80 | KDM4E (0.47) | RAB9ANPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL2917221 | 0.75 | ALDH1A1 (0.61) | RAB9ANPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL11620226 | 0.74 | ALDH1A1 (0.46) | RAB9ANPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL11619286 | 0.74 | KDM4E (0.52) | RAB9ANPC1HPGDKDM4EALDH1A1 | |
| SCHEMBL11620021 | 0.72 | RAB9A (0.43) | RAB9ANPC1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |