SCHEMBL11620219

SCHEMBL11620219

CCCSSc1cc(C)oc1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11622877 0.84 KDM4E (0.33) KDM4EMAPT
SCHEMBL11686616 0.80 KDM4E (0.32) KDM4EMAPT
SCHEMBL3508454 0.79 NQO1 (0.38) KDM4EMAPT
SCHEMBL424992 0.73 NPC1 (0.37) KDM4E
SCHEMBL4572609 0.71 ALDH1A1 (0.37) KDM4EMAPT
SCHEMBL5163702 0.69 NQO1 (0.38) KDM4EMAPT
SCHEMBL3505875 0.69 DDB1 (0.33) KDM4E
SCHEMBL4572610 0.68
SCHEMBL11621777 0.66
SCHEMBL11445495 0.65 KMT2A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4107184-A MODIFYING ORGANOLEPTIC PROPERTIES OF FOODSTUFFS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-08-15 US disclosed
US-4098910-A FLAVORING WITH CERTAIN 3-FURYL ALKYL DISULFIDES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-07-04 US disclosed