Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842902 | 0.92 | MEN1 (0.34) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL27899868 | 0.91 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11619402 | 0.90 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11842899 | 0.85 | GAA (0.35) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11619260 | 0.81 | POLB (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11620053 | 0.80 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11622252 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL6354671 | 0.75 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL18398288 | 0.75 | KCNJ11 (0.37) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11618263 | 0.75 | KDM4E (0.49) | ALDH1A1RAB9AHTTL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |