Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11619408 | 0.91 | ALDH1A1 (0.43) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11620053 | 0.83 | ALDH1A1 (0.39) | POLBALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11622252 | 0.82 | ALDH1A1 (0.39) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11620240 | 0.81 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL11619273 | 0.81 | HPGD (0.43) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11624619 | 0.80 | ALOX15 (0.46) | POLBALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL11619423 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL11622953 | 0.76 | MEP1B (0.40) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11622343 | 0.75 | ALDH1A1 (0.41) | POLBALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11619296 | 0.75 | POLB (0.41) | POLBALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |