Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443819 | 0.82 | TLR8 (0.43) | ALDH1A1LMNAKDM4EALOX15PDGFRB | |
| SCHEMBL28627967 | 0.78 | ALOX15 (0.43) | ALDH1A1LMNAKDM4EGAAALOX15 | |
| SCHEMBL7540702 | 0.77 | KDM4E (0.46) | ALDH1A1LMNAKDM4EGAAALOX15 | |
| SCHEMBL27463979 | 0.77 | CDK1 (0.41) | ALDH1A1LMNAKDM4EGAAALOX15 | |
| SCHEMBL27293614 | 0.77 | AR (0.45) | ALDH1A1LMNAKDM4EGAAL3MBTL1 | |
| SCHEMBL23719266 | 0.76 | ERBB2 (0.43) | ALDH1A1KDM4EGAAALOX15MAPT | |
| SCHEMBL15202406 | 0.76 | ALOX15 (0.41) | ALDH1A1KDM4EGAAALOX15L3MBTL1 | |
| SCHEMBL8736424 | 0.76 | ALOX15 (0.41) | ALDH1A1LMNAKDM4EGAAALOX15 | |
| SCHEMBL28176277 | 0.75 | CDK2 (0.47) | CHEK1FGFR1CDK2KDRMAPT | |
| SCHEMBL2449809 | 0.75 | ALOX15 (0.48) | ALDH1A1LMNAKDM4EGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1680333-A | Anti-virus pyrazole derivatives | HOFFMANN LA ROCHE (CH) | 2005-10-12 | — | — | CN | claimed |
| CN-1469865-A | Pyrazole derivatives for the treatment of viral diseases | - | 2004-01-21 | — | — | CN | claimed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |