Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.93 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.93 |
| ▸ | HTR7 | P34969 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | USP7 | Q93009 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | HTR1E | P28566 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | HTR6 | P50406 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513073 | 0.98 | LMNA (0.90) | LMNAMAPK10HTR7MAPTHPGD | |
| SCHEMBL646266 | 0.96 | LMNA (1.00) | LMNAMAPK10HTR7MAPTHPGD | |
| SCHEMBL4471607 | 0.82 | MAPT (0.93) | LMNAMAPK10HTR7MAPTHPGD | |
| SCHEMBL20546703 | 0.82 | HTR7 (1.00) | LMNAMAPK10HTR7HTR1DHTR2A | |
| SCHEMBL23722539 | 0.82 | LMNA (0.64) | LMNAMAPK10HTR7MAPTHPGD | |
| SCHEMBL1250659 | 0.79 | LMNA (0.60) | LMNAMAPK10HTR7NPSR1 | |
| SCHEMBL2851304 | 0.77 | HTR7 (0.79) | LMNAMAPK10HTR7HTR1DHTR2A | |
| SCHEMBL10818201 | 0.77 | HTR7 (0.79) | LMNAMAPK10HTR7HTR1DHTR2A | |
| SCHEMBL10296211 | 0.76 | MAPT (0.59) | LMNAMAPK10HTR7MAPTHPGD | |
| SCHEMBL12643304 | 0.76 | LMNA (0.61) | LMNAMAPK10HTR7MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238173-A1 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 INHIBITORS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2021-08-05 | — | — | US | disclosed |
| EP-3802498-A1 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 INHIBITORS | Yeda Research and Development Co. Ltd (IL) | 2021-04-14 | — | — | EP | disclosed |
| CN-112236414-A | Mitogen-activated protein kinase 7 inhibitors | 耶达研究及发展有限公司 | 2021-01-15 | — | — | CN | disclosed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238173-A1 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 INHIBITORS | MAPK7, MAP2K7, MAP3K7 | LMNA 2172/4885MAPK10 50/4885HTR7 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.