Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626377 | 0.86 | LMNA (0.54) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11791163 | 0.85 | LMNA (0.53) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11796025 | 0.85 | TLR8 (0.44) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11626843 | 0.83 | MAPT (0.51) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11625245 | 0.82 | LMNA (0.50) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11727584 | 0.80 | LMNA (0.49) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11796088 | 0.76 | LMNA (0.54) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11624572 | 0.76 | LMNA (0.54) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11791205 | 0.75 | ALDH1A1 (0.43) | LMNAHSD17B10TSHRTP53SMN1; SMN2 | |
| SCHEMBL11810062 | 0.75 | MAPT (0.41) | LMNAHSD17B10TSHRTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070362-A | CNS DEPRESSANTS, ANTIINFLAMMATORY AGENTS, CYCLIC 3', 5'-AMP STIMULANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-01-24 | — | — | US | disclosed |