Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619104 | 0.86 | RORC (0.62) | RORCSMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL9756597 | 0.85 | RORC (0.56) | RORCSMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL10577425 | 0.85 | EPHX1 (0.46) | SMN1; SMN2POLBL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL27916473 | 0.83 | RORC (0.55) | RORCSMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL1906950 | 0.82 | RORC (0.54) | RORCSMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL27820437 | 0.81 | RORC (0.56) | RORCSMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL16620122 | 0.80 | EPHX2 (0.57) | SMN1; SMN2L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL7366510 | 0.79 | CA12 (0.44) | SMN1; SMN2POLBIDO1MEN1KMT2A | |
| SCHEMBL4548035 | 0.78 | EPHX1 (0.70) | RORCSMN1; SMN2POLBIDO1MEN1 | |
| SCHEMBL11000061 | 0.78 | KMT2A (0.69) | L3MBTL1ALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |