Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA5A | P35218 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815301 | 0.89 | ALDH1A1 (0.65) | EPHX1EPHX2IDO1MEN1KMT2A | |
| SCHEMBL864429 | 0.84 | SMN1; SMN2 (0.79) | EPHX2CA2NPC1MEN1KMT2A | |
| SCHEMBL31198183 | 0.84 | HSD17B10 (0.59) | EPHX2CYP3A4CA2CA4CA9 | |
| SCHEMBL5674663 | 0.84 | HSD17B10 (0.59) | EPHX2CYP3A4CA2CA4CA9 | |
| SCHEMBL3786387 | 0.84 | CA1 (0.58) | CA2CA9NPC1MEN1KMT2A | |
| SCHEMBL405569 | 0.84 | SMN1; SMN2 (0.59) | EPHX1EPHX2NPC1KMT2ALMNA | |
| SCHEMBL13602308 | 0.84 | SMN1; SMN2 (0.59) | EPHX1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL31349930 | 0.84 | SMN1; SMN2 (0.79) | EPHX2CA2NPC1MEN1KMT2A | |
| SCHEMBL10814711 | 0.84 | GAA (0.66) | EPHX1EPHX2CYP3A4APEX1CA2 | |
| SCHEMBL3791892 | 0.84 | ALDH1A1 (0.60) | EPHX1MEN1KMT2AMAPTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091978-A1 | A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE | AMOGH CHEMICALS PVT. LTD (IN) | 2018-05-24 | — | — | WO | claimed |
| CN-105130872-B | Preparation method of 3-trifluoromethyl substituted indole | 江西师范大学 | 2018-01-30 | — | — | CN | claimed |
| US-11731933-B2 | Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid | ADIONICS (FR) | 2023-08-22 | — | — | US | disclosed |
| CN-112574054-B | Efficient nitriding reagent and application thereof | 北京大学 | 2022-10-14 | — | — | CN | disclosed |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2021-06-10 | — | — | US | disclosed |
| CN-112574054-A | Efficient nitriding reagent and application thereof | 北京大学 | 2021-03-30 | — | — | CN | disclosed |
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |
| CN-108069868-B | Method for preparing organic amide compound from aryl diazo tetrafluoroborate and nitrile | 湖南理工学院 | 2020-11-13 | — | — | CN | disclosed |
| WO-2018091978-A1 | A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE | AMOGH CHEMICALS PVT. LTD (IN) | 2018-05-24 | — | — | WO | disclosed |
| WO-2018091978-A1 | A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE | AMOGH CHEMICALS PVT. LTD (IN) | 2018-05-24 | — | — | WO | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5646085-A | AMINATION | RHONE-POULENC CHIMIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-4600797-A | NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | disclosed |
| EP-0049711-B1 | PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES | BAYER AG (DE) | 1984-02-29 | — | — | EP | disclosed |
| EP-0049711-A1 | Process for the production of nitro-amino-benzenes | BAYER AG (DE) | 1982-04-21 | — | — | EP | disclosed |
| US-4160017-A | EMETIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731933-B2 | Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid | AQP3, AQP1, AQP4 | EPHX1 2588/4885EPHX2 1663/4885CYP3A4 4048/4885 |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | XDH, PNPO, AGXT | EPHX1 405/4885EPHX2 818/4885CYP3A4 852/4885 |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | EPHX1 405/4885EPHX2 818/4885CYP3A4 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.