Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620013 | 0.91 | SMN1; SMN2 (0.37) | SMN1; SMN2GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11622854 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11620869 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11622537 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11625646 | 0.81 | KMT2A (0.37) | SMN1; SMN2GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11623223 | 0.80 | KMT2A (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11622045 | 0.80 | LMNA (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11621699 | 0.77 | KMT2A (0.39) | SMN1; SMN2MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL11616963 | 0.76 | MEN1 (0.37) | SMN1; SMN2GRIN2BMEN1KMT2AALDH1A1 | |
| SCHEMBL11622946 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2GRIN2BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |