Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621488 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1GRIN2BHPGD | |
| SCHEMBL11625646 | 0.89 | KMT2A (0.37) | SMN1; SMN2KMT2AMEN1GRIN2BLMNA | |
| SCHEMBL11623223 | 0.88 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1LMNAGAA | |
| SCHEMBL11621699 | 0.88 | KMT2A (0.39) | SMN1; SMN2KMT2AMEN1LMNAGAA | |
| SCHEMBL11622924 | 0.86 | CNR1 (0.39) | KMT2ALMNAKDM4EALDH1A1NPSR1 | |
| SCHEMBL9876893 | 0.86 | PTGIR (0.43) | SMN1; SMN2KMT2AMEN1LMNAHPGD | |
| SCHEMBL11622691 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2AMEN1GRIN2BLMNA | |
| SCHEMBL11622045 | 0.85 | LMNA (0.44) | SMN1; SMN2KMT2AMEN1LMNAHPGD | |
| SCHEMBL11620762 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1GRIN2BLMNA | |
| SCHEMBL11624052 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |