Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624474 | 0.88 | KDM1A (0.49) | ALDH1A1KDM1APSMB8PSMB5MAOA | |
| SCHEMBL11627596 | 0.86 | FLT1 (0.52) | ALDH1A1KDM1AMAOALMNA | |
| SCHEMBL11625380 | 0.86 | MEN1 (0.55) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL11626120 | 0.85 | CA1 (0.57) | ALDH1A1KDM1AMAPTKCNA5 | |
| SCHEMBL11629012 | 0.82 | MAPT (0.61) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL11625369 | 0.77 | HRH3 (0.52) | ALDH1A1POLBKDM1AMEN1KMT2A | |
| SCHEMBL11631171 | 0.77 | HRH3 (0.52) | ALDH1A1POLBKDM1AMEN1KMT2A | |
| SCHEMBL11627196 | 0.77 | ALDH1A1 (0.47) | ALDH1A1POLBKDM1ATP53BP1MEN1 | |
| SCHEMBL3243689 | 0.76 | ALDH1A1 (0.68) | ALDH1A1POLBTP53BP1LMNA | |
| SCHEMBL11627591 | 0.76 | ALDH1A1 (0.48) | ALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066639-A | BENZENE-SULFONYL SEMICARBAZIDES AND PROCESS FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |