Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624474 | 0.88 | KDM1A (0.49) | KDM1ACA1CA2ALDH1A1LMNA | |
| SCHEMBL11625380 | 0.87 | MEN1 (0.55) | CA1CA2PPARAALDH1A1LMNA | |
| SCHEMBL11626120 | 0.87 | CA1 (0.57) | KDM1ACA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11623182 | 0.86 | ALDH1A1 (0.52) | KDM1AALDH1A1LMNAMAOA | |
| SCHEMBL11627098 | 0.84 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11626679 | 0.83 | FLT1 (0.51) | FLT1FLT4KDRKDM1ACA1 | |
| SCHEMBL11630984 | 0.82 | NLRP3 (0.62) | FLT1FLT4KDRNLRP3ALDH1A1 | |
| SCHEMBL11624745 | 0.82 | NLRP3 (0.74) | NLRP3ALDH1A1LMNA | |
| SCHEMBL11629012 | 0.81 | MAPT (0.61) | CA1CA2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11624959 | 0.80 | NLRP3 (0.60) | NLRP3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066639-A | BENZENE-SULFONYL SEMICARBAZIDES AND PROCESS FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |