Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.62 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.51 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439603 | 0.85 | RAB9A (0.47) | GSK3BMAPTALDH1A1CYP1A2BLM | |
| SCHEMBL23014249 | 0.84 | MEN1 (0.51) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5640455 | 0.84 | GSK3B (0.50) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6768977 | 0.83 | ALDH1A1 (0.61) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14830961 | 0.81 | ERCC5 (0.58) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6200322 | 0.81 | MEN1 (0.62) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20245318 | 0.81 | ALDH1A1 (0.50) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20245364 | 0.81 | KMT2A (0.48) | GSK3BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22570668 | 0.81 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL22570705 | 0.80 | TSHR (0.43) | GSK3BMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123541-A | ANTIINFLAMMATORY AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-10-31 | — | — | US | disclosed |
| US-4101660-A | ANTIIFLAMMATORY AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-07-18 | — | — | US | disclosed |