Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623239 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL11602755 | 0.85 | GRIA2 (0.41) | SMN1; SMN2TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL11626807 | 0.83 | P2RX7 (0.39) | SMN1; SMN2TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10513666 | 0.82 | GRIA2 (0.40) | SMN1; SMN2TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10513431 | 0.82 | TSHR (0.51) | SMN1; SMN2TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL11603593 | 0.82 | FPR2 (0.40) | SMN1; SMN2TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL11474480 | 0.78 | GRIA2 (0.37) | ALDH1A1LMNATDP1MAPTGRIA2 | |
| SCHEMBL10771495 | 0.78 | MAPT (0.35) | SMN1; SMN2TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL10513001 | 0.77 | GRIA2 (0.36) | HTR2CTDP1GRIA2MEN1KMT2A | |
| SCHEMBL10512479 | 0.76 | GRIA2 (0.36) | TSHRHTR2AHTR2CHTR2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115102-A | PYRIDYLOXYPHENOXYALKANE CARBOXYLIC ACIDS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1978-09-19 | — | — | US | claimed |