Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355765 | 0.93 | GAA (0.34) | GAAMMP13RAB9ASMN1; SMN2HPGD | |
| SCHEMBL20399794 | 0.91 | ALDH1A1 (0.36) | GAAMMP13RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14359375 | 0.89 | ALDH1A1 (0.38) | GAAHPGDMAPK1TDP1ALDH1A1 | |
| SCHEMBL20399711 | 0.77 | ALDH1A1 (0.35) | MMP13ALDH1A1ADAMTS5 | |
| SCHEMBL11021412 | 0.75 | GAA (0.36) | GAAMMP13RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15974332 | 0.75 | GAA (0.36) | GAAMMP13RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8958230 | 0.75 | GAA (0.36) | GAAMMP13RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11865054 | 0.74 | ALOX12 (0.34) | GAATDP1ALDH1A1HSD11B1MAPT | |
| SCHEMBL5447079 | 0.73 | GAA (0.42) | GAAMMP13RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15974011 | 0.72 | GAA (0.36) | GAAMMP13RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071477-A | CASTING AND LAMINATING RESINS | CIBA-GEIGY CORPORATION (US) | 1978-01-31 | — | — | US | disclosed |