Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623896 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL11726838 | 0.86 | CA12 (0.50) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL18806465 | 0.85 | RECQL (0.62) | ALDH1A1MEN1KMT2ACA12RECQL | |
| SCHEMBL11723680 | 0.84 | AR (0.51) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL11721772 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL8664384 | 0.83 | CA12 (0.59) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL11616626 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTCA12RECQLCA9 | |
| SCHEMBL11724682 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2ACA12RECQL | |
| SCHEMBL11721609 | 0.82 | CA12 (0.46) | ALDH1A1MAPTMEN1KMT2ACA12 | |
| SCHEMBL11726568 | 0.82 | CA12 (0.52) | ALDH1A1MAPTMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124593-A | ANTICONVULSANTS, EPILEPSY | CIBA-GEIGY CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |
| US-4025505-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-3941883-A | Aromatic dicarboxamides as anticonvulsants | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |