Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584675 | 0.89 | CA12 (0.61) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL11726838 | 0.85 | CA12 (0.50) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL28911652 | 0.84 | CA12 (0.70) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL9468297 | 0.84 | SCN2A (0.64) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL28960739 | 0.83 | CA12 (0.64) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL18806465 | 0.83 | RECQL (0.62) | CA12ALDH1A1SCN2AMEN1KMT2A | |
| SCHEMBL11623903 | 0.83 | ALDH1A1 (0.55) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL11723680 | 0.83 | AR (0.51) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL11721609 | 0.81 | CA12 (0.46) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL11724682 | 0.81 | ALDH1A1 (0.53) | CA12ALDH1A1KMT2AMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853635-A1 | BRANCHED BLOCK ETHYLENE POLYMERS, THEIR PREPARATION AND COMPOSITIONS COMPRISING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997012919-A1 | BRANCHED BLOCK ETHYLENE POLYMERS, THEIR PREPARATION AND COMPOSITIONS COMPRISING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1997-04-10 | — | — | WO | disclosed |