Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624212 | 0.88 | NPC1 (0.55) | MAPTNPC1ALDH1A1DRD4GFER | |
| SCHEMBL11622963 | 0.85 | KDM4E (0.56) | MAPTNPC1ALDH1A1DRD4DRD5 | |
| SCHEMBL11624817 | 0.85 | GFER (0.68) | MAPTNPC1ALDH1A1DRD4GFER | |
| SCHEMBL11627660 | 0.83 | ALDH1A1 (0.55) | MAPTNPC1ALDH1A1DRD4KDM4E | |
| SCHEMBL28694820 | 0.82 | ALDH1A1 (0.52) | MAPTNPC1ALDH1A1GFERKDM4E | |
| SCHEMBL11622300 | 0.82 | KDM4E (0.49) | MAPTDRD4DRD5POLBGFER | |
| SCHEMBL11622589 | 0.81 | DRD4 (0.53) | MAPTNPC1ALDH1A1DRD4GFER | |
| SCHEMBL15347357 | 0.80 | POLB (0.58) | NPC1ALDH1A1POLB | |
| SCHEMBL31349213 | 0.77 | POLB (0.60) | MAPTALDH1A1DRD4DRD5POLB | |
| SCHEMBL8263606 | 0.76 | ALDH1A1 (0.63) | NPC1ALDH1A1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123529-A | TREATMENT OF ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1978-10-31 | — | — | US | disclosed |