Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624212 | 0.85 | NPC1 (0.55) | ALDH1A1MAPTDRD2DRD4NPC1 | |
| SCHEMBL11623927 | 0.83 | MAPT (0.52) | ALDH1A1KDM4EMAPTDRD4NPC1 | |
| SCHEMBL11622963 | 0.83 | KDM4E (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2DRD4 | |
| SCHEMBL11627858 | 0.83 | MAPT (0.52) | ALDH1A1KDM4EMAPTHTTTDP1 | |
| SCHEMBL11624817 | 0.82 | GFER (0.68) | ALDH1A1MAPTDRD2SMN1; SMN2DRD4 | |
| SCHEMBL11625921 | 0.82 | MAPT (0.58) | ALDH1A1KDM4EMAPTHTTTDP1 | |
| SCHEMBL13219624 | 0.80 | POLB (0.60) | ALDH1A1KDM4EMAPTHTTTDP1 | |
| SCHEMBL28694820 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2NPC1 | |
| SCHEMBL11622589 | 0.79 | DRD4 (0.53) | ALDH1A1MAPTDRD2DRD4NPC1 | |
| SCHEMBL11624446 | 0.78 | MAPT (0.58) | ALDH1A1MAPTSMN1; SMN2HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123529-A | TREATMENT OF ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1978-10-31 | — | — | US | disclosed |