Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 20/20 | 0.59 |
| ▸ | ABCC9 | O60706 | 7/20 | 0.59 |
| ▸ | ABCC8 | Q09428 | 7/20 | 0.59 |
| ▸ | KCNJ8 | Q15842 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623939 | 0.90 | KCNJ11 (0.73) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL11627211 | 0.86 | KCNJ11 (0.60) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL11627766 | 0.81 | KCNJ11 (0.42) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL11627338 | 0.76 | KCNJ11 (0.46) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL11627210 | 0.76 | KCNJ11 (0.75) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL11628632 | 0.75 | NLRP3 (0.45) | KCNJ11 | |
| SCHEMBL7117829 | 0.74 | KCNJ11 (1.00) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL7118071 | 0.73 | KCNJ11 (1.00) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL29405861 | 0.72 | KCNJ11 (1.00) | KCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL4260449 | 0.72 | KCNJ11 (1.00) | KCNJ11ABCC9ABCC8KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093742-A | Anti-hypertensive polyhaloisopropyl-substituted arylureas | SCHERING CORPORATION (US) | 1978-06-06 | — | — | US | claimed |