Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.64 |
| ▸ | DRD4 | P21917 | 7/20 | 0.64 |
| ▸ | DRD3 | P35462 | 6/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626434 | 0.89 | DRD2 (0.52) | DRD2DRD4DRD3HTR2AHRH1 | |
| SCHEMBL11621546 | 0.88 | DRD2 (0.51) | DRD2DRD4DRD3HTR2AHRH1 | |
| SCHEMBL11624111 | 0.85 | DRD2 (0.53) | DRD2DRD4DRD3HTR2AHRH1 | |
| SCHEMBL11622269 | 0.83 | DRD4 (0.70) | DRD2DRD4DRD3HTR7KDM4E | |
| Hydrochloric Acid SCHEMBL11624621 | 0.82 | DHFR (0.53) | DRD2HTR2AHRH1HTR7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11623997 | 0.81 | DRD2 (0.50) | DRD2DRD4DRD3HTR2AHRH1 | |
| SCHEMBL1136711 | 0.79 | DRD4 (0.71) | DRD2DRD4DRD3HTR2AHTR7 | |
| SCHEMBL11623344 | 0.78 | DRD4 (0.66) | DRD2DRD4DRD3HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL11624630 | 0.77 | DRD4 (0.61) | DRD2DRD4DRD3HTR7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11625928 | 0.76 | DRD2 (0.43) | DRD2DRD4DRD3HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4123529-A | TREATMENT OF ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1978-10-31 | — | — | US | disclosed |