Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527934 | 0.98 | — | — | |
| SCHEMBL1969772 | 0.79 | TSHR (0.55) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL1401795 | 0.76 | TSHR (0.52) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL28313918 | 0.74 | CRBN (0.43) | TSHRKMT2AGAAKDM4EPOLB | |
| SCHEMBL4751064 | 0.74 | TSHR (0.50) | TSHRGSK3AGSK3BABL1LMNA | |
| SCHEMBL14233263 | 0.73 | — | — | |
| SCHEMBL11483737 | 0.73 | — | — | |
| SCHEMBL181570 | 0.73 | — | — | |
| SCHEMBL1406517 | 0.73 | — | — | |
| SCHEMBL4597653 | 0.73 | TSHR (1.00) | TSHRGSK3AGSK3BABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073924-A | Hydantoin derivatives and broad spectrum bactericidal/fungicidal compositions thereof | GLYCO CHEMICALS, INC. (US) | 1978-02-14 | — | — | US | disclosed |