Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202796 | 0.85 | TSHR (0.72) | TSHRGSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL9212290 | 0.82 | TSHR (0.69) | TSHRGSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL11022512 | 0.82 | TSHR (0.69) | TSHRGSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL13629854 | 0.81 | TSHR (0.68) | TSHRGSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL11020365 | 0.79 | TSHR (0.66) | TSHRGSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL2485668 | 0.78 | TSHR (0.63) | TSHRGSK3AGSK3BALDH1A1POLB | |
| SCHEMBL20393489 | 0.78 | TSHR (0.63) | TSHRGSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL7454709 | 0.78 | TSHR (0.63) | TSHRGSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL6773573 | 0.76 | TSHR (0.61) | TSHRGSK3AGSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL2527934 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344597-B2 | Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-07-01 | — | — | US | disclosed |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | THE SCRIPPS RESEARCH INSTITUTE | 2024-04-02 | — | — | US | disclosed |
| CN-112236424-B | Alkoxy-substituted pyridinyl derivatives | 爱杜西亚药品有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-11851449-B2 | Heterocyclic amide compounds having an RORvt inhibitory action | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-26 | — | — | US | disclosed |
| EP-3018123-B1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2023-05-10 | — | — | EP | disclosed |
| EP-3802517-B1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-12-21 | — | — | EP | disclosed |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | THE SCRIPPS RESEARCH INSTITUTE | 2022-06-30 | — | — | US | disclosed |
| CN-114127050-A | Benzopyran and imidazole derivatives useful for stabilizing amyloidogenic immunoglobulin light chains | 斯克利普斯研究所 | 2022-03-01 | — | — | CN | disclosed |
| EP-3946604-A1 | BENZOPYRANE AND IMIDAZOLE DERIVATIVES USEFUL FOR THE STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | The Scripps Research Institute (US) | 2022-02-09 | — | — | EP | disclosed |
| US-20210277030-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-09-09 | — | — | US | disclosed |
| US-5912261-A | ANTIDIABETIC AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-15 | — | — | US | disclosed |
| CN-1206005-A | Novel inhibitors of bone resorption and antagonists of vitronectin receptors | HOECHST AG (DE) | 1999-01-27 | — | — | CN | disclosed |
| EP-0796855-A1 | Inhibitors of bone resorption and vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-24 | — | — | EP | disclosed |
| US-5389614-A | Anticoagulants | CASSELLA AG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0048834-B1 | METHOD FOR MEASUREMENT OF TRACE ENZYMES | FUJI PHOTO FILM CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0047470-B1 | METHOD FOR IMMUNOCHEMICAL MEASUREMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4473652-A | LABELLING WITH CYANINE OR MEROCYANINE DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-25 | — | — | US | disclosed |
| US-4414325-A | PHOTOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| EP-0048834-A1 | Method for measurement of trace enzymes | FUJI PHOTO FILM CO., LTD. (JP) | 1982-04-07 | — | — | EP | disclosed |
| EP-0047470-A1 | Method for immunochemical measurement | FUJI PHOTO FILM CO., LTD. (JP) | 1982-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344597-B2 | Alkoxy-substituted pyridinyl derivatives as LPA1 receptor antagonists and their use in the treatment of fibrosis | LPAR1, LPAR3, LPAR2 | TSHR 542/4885GSK3A 1913/4885GSK3B 1770/4885 |
| US-20220204485-A1 | STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS | TTR, MAP1LC3B, SAAL1 | TSHR 3610/4885GSK3A 3168/4885GSK3B 3051/4885 |
| US-20210277030-A1 | AMIDE COMPOUND | RORB, RORC, RORA | TSHR 919/4885GSK3A 1736/4885GSK3B 1593/4885 |
| US-11851449-B2 | Heterocyclic amide compounds having an RORvt inhibitory action | RORB, RORC, RORA | TSHR 397/4885GSK3A 1488/4885GSK3B 1448/4885 |
| US-11945806-B2 | Stabilization of amyloidogenic immunoglobulin light chains | TTR, MAP1LC3B, SAAL1 | TSHR 3610/4885GSK3A 3168/4885GSK3B 3051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.