Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448906 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL10733230 | 0.87 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11663270 | 0.85 | TDP1 (0.54) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11628716 | 0.85 | TSHR (0.58) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL15646534 | 0.85 | TSHR (0.54) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11622460 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11518080 | 0.84 | FFAR4 (0.56) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11844196 | 0.84 | FFAR4 (0.43) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL5033435 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL10741844 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069325-A | 3-Carbalkoxyamino-1H-2,1,4-benzothiadiazine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
| US-3996368-A | Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |